验证数据展示
产品信息
67371-1-PBS targets TBXAS1 in Indirect ELISA, IHC, WB applications and shows reactivity with pig, mouse, human samples.
经测试应用 | Indirect ELISA, IHC, WB Application Description |
经测试反应性 | pig, mouse, human |
免疫原 | TBXAS1 fusion protein Ag29177 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | thromboxane A synthase 1 (platelet) |
别名 | Hydroperoxy icosatetraenoate dehydratase, EC:5.3.99.5, EC:4.2.1.152, CYP5A1, CYP5 |
计算分子量 | 60 kDa |
观测分子量 | 52 kDa |
GenBank蛋白编号 | BC014117 |
基因名称 | TBXAS1 |
Gene ID (NCBI) | 6916 |
RRID | AB_2918487 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P24557 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TBXAS1 catalyzes the conversion of the prostaglandin endoperoxide into thromboxane A2 as a potent vasoconstrictor and inducer of platelet aggregation.It was identified as novel airway fibroblast-specific markers with integrin-8 (ITGA8) (PMID:20435685). It was observed in the epithelium.It is a monomer with the molecular weight of 60 KDa. It also has two variants with 60.5 kDa and 52.3 kDa (PMID:1730669). It also reavels a molecular weight of 55 kDa in humen uterus (PMID:1386258).