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  • Featured Product
  • KD/KO Validated

TBXAS1 Monoclonal antibody, PBS Only

TBXAS1 Monoclonal Antibody for Indirect ELISA, IHC, WB

Host / Isotype

Mouse / IgG2a

Reactivity

pig, mouse, human

Applications

Indirect ELISA, IHC, WB

Conjugate

Unconjugated

CloneNo.

1F6G6

Cat No : 67371-1-PBS

Print datasheet

Synonyms

Hydroperoxy icosatetraenoate dehydratase, EC:5.3.99.5, EC:4.2.1.152, CYP5A1, CYP5

验证数据展示

  • WB analysis of human peripheral blood platelets using 67371-1-Ig (same clone as 67371-1-PBS)

    WB analysis of human peripheral blood platelets using 67371-1-Ig (same clone as 67371-1-PBS)

    Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67371-1-Ig (TBXAS1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67371-1-PBS in a different storage buffer formulation.

  • WB analysis of A549 using 67371-1-Ig (same clone as 67371-1-PBS)

    WB analysis of A549 using 67371-1-Ig (same clone as 67371-1-PBS)

    WB result of TBXAS1 antibody (67371-1-Ig; 1:5000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TBXAS1 transfected A549 cells. This data was developed using the same antibody clone with 67371-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 67371-1-Ig (same clone as 67371-1-PBS)

    IHC staining of human lung cancer using 67371-1-Ig (same clone as 67371-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67371-1-Ig (TBXAS1 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67371-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 67371-1-Ig (same clone as 67371-1-PBS)

    IHC staining of human lung cancer using 67371-1-Ig (same clone as 67371-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67371-1-Ig (TBXAS1 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67371-1-PBS in a different storage buffer formulation.

  • FC experiment of A549 using 67371-1-Ig (same clone as 67371-1-PBS)

    FC experiment of A549 using 67371-1-Ig (same clone as 67371-1-PBS)

    1x10^6 A549 cells were intracellularly stained with 0.8 ug TBXAS1 Monoclonal antibody (67371-1-Ig, Clone:1F6G6) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1)(red), or 0.8 ug Mouse IgG2a isotype control Mouse McAb (66360-2-Ig, Clone: 11A1B2) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 67371-1-PBS in a different storage buffer formulation.

产品信息

67371-1-PBS targets TBXAS1 in Indirect ELISA, IHC, WB applications and shows reactivity with pig, mouse, human samples.

Tested Applications Indirect ELISA, IHC, WB Application Description
Tested Reactivity pig, mouse, human
Immunogen TBXAS1 fusion protein Ag29177 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name thromboxane A synthase 1 (platelet)
Synonyms Hydroperoxy icosatetraenoate dehydratase, EC:5.3.99.5, EC:4.2.1.152, CYP5A1, CYP5
Calculated Molecular Weight 60 kDa
Observed Molecular Weight 52 kDa
GenBank Accession NumberBC014117
Gene Symbol TBXAS1
Gene ID (NCBI) 6916
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP24557
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TBXAS1 catalyzes the conversion of the prostaglandin endoperoxide into thromboxane A2 as a potent vasoconstrictor and inducer of platelet aggregation.It was identified as novel airway fibroblast-specific markers with integrin-8 (ITGA8) (PMID:20435685). It was observed in the epithelium.It is a monomer with the molecular weight of 60 KDa. It also has two variants with 60.5 kDa and 52.3 kDa (PMID:1730669). It also reavels a molecular weight of 55 kDa in humen uterus (PMID:1386258).