验证数据展示
产品信息
68164-1-PBS targets TCEB1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | Human, mouse, rat |
Immunogen | TCEB1 fusion protein Ag22601 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
Synonyms | EloC, Elongin 15 kDa subunit, Elongin C, SIII, SIII p15, TCEB1 |
Calculated Molecular Weight | 112 aa, 12 kDa |
Observed Molecular Weight | 12 kDa |
GenBank Accession Number | BC013809 |
Gene Symbol | TCEB1 |
Gene ID (NCBI) | 6921 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q15369 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TCEB1, also named as RNA polymerase II transcription factor SIII subunit C, belongs to the SKP1 family. It mediates the ubiquitination of ECS-E3 ubiquitin-protein ligase complexes. TCEB1 is overexpressed in prostate cancer cell line PC-3 and breast cancer cell line SK-BR-3. TCEB1 also promotes invasion of prostate cancer cells (PMID:18844214).