验证数据展示
产品信息
68164-1-PBS targets TCEB1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat |
免疫原 | TCEB1 fusion protein Ag22601 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
别名 | EloC, Elongin 15 kDa subunit, Elongin C, SIII, SIII p15, TCEB1 |
计算分子量 | 112 aa, 12 kDa |
观测分子量 | 12 kDa |
GenBank蛋白编号 | BC013809 |
基因名称 | TCEB1 |
Gene ID (NCBI) | 6921 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q15369 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TCEB1, also named as RNA polymerase II transcription factor SIII subunit C, belongs to the SKP1 family. It mediates the ubiquitination of ECS-E3 ubiquitin-protein ligase complexes. TCEB1 is overexpressed in prostate cancer cell line PC-3 and breast cancer cell line SK-BR-3. TCEB1 also promotes invasion of prostate cancer cells (PMID:18844214).