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验证数据展示

  • IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 14519-1-AP (TCF7L1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 14519-1-AP (TCF7L1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

  • WB analysis using 14519-1-AP (same clone as 14519-1-PBS)

    WB analysis using 14519-1-AP (same clone as 14519-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14519-1-AP (TCF7L1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 14519-1-AP (same clone as 14519-1-PBS)

    IF Staining of U2OS using 14519-1-AP (same clone as 14519-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TCF7L1 antibody (14519-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

TCF7L1 Polyclonal antibody, PBS Only

TCF7L1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 14519-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

14519-1-PBS targets TCF7L1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TCF7L1 fusion protein Ag5983 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transcription factor 7-like 1 (T-cell specific, HMG-box)
别名
计算分子量 63 kDa
观测分子量 63-70 kDa
GenBank蛋白编号BC058894
基因名称 TCF7L1
Gene ID (NCBI) 83439
RRIDAB_2287033
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9HCS4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TCF7L1 is one of TCF/LEF transcription factors that are mediators of the Wnt signaling pathway and are antagonized by the TGF-beta signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It's necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis