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TCF7L1 Polyclonal antibody, PBS Only

TCF7L1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14519-1-PBS

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Synonyms

验证数据展示

  • IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 14519-1-AP (TCF7L1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    IHC staining of human breast cancer using 14519-1-AP (same clone as 14519-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 14519-1-AP (TCF7L1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

  • WB analysis using 14519-1-AP (same clone as 14519-1-PBS)

    WB analysis using 14519-1-AP (same clone as 14519-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14519-1-AP (TCF7L1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 14519-1-AP (same clone as 14519-1-PBS)

    IF Staining of U2OS using 14519-1-AP (same clone as 14519-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TCF7L1 antibody (14519-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 14519-1-PBS in a different storage buffer formulation.

产品信息

14519-1-PBS targets TCF7L1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen TCF7L1 fusion protein Ag5983 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transcription factor 7-like 1 (T-cell specific, HMG-box)
Synonyms
Calculated Molecular Weight 63 kDa
Observed Molecular Weight 63-70 kDa
GenBank Accession NumberBC058894
Gene Symbol TCF7L1
Gene ID (NCBI) 83439
RRIDAB_2287033
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9HCS4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TCF7L1 is one of TCF/LEF transcription factors that are mediators of the Wnt signaling pathway and are antagonized by the TGF-beta signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It's necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis