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TCF7L1/TCF7L2 Monoclonal antibody, PBS Only

TCF7L1/TCF7L2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B2D12

Cat no : 67652-1-PBS

Print datasheet

Synonyms

HMG box transcription factor 3, HMG box transcription factor 4, TCF 3, TCF 4, TCF3, TCF4, TCF7L1, TCF7L2, Transcription factor 7 like 1

验证数据展示

  • WB analysis using 67652-1-Ig (same clone as 67652-1-PBS)

    WB analysis using 67652-1-Ig (same clone as 67652-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67652-1-Ig (TCF7L1/TCF7L2 antibody) at dilution of 1:50000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67652-1-PBS in a different storage buffer formulation.

产品信息

67652-1-PBS targets TCF7L1/TCF7L2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, Mouse
Immunogen TCF7L1/TCF7L2 fusion protein Ag28954 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name transcription factor 7-like 1 (T-cell specific, HMG-box)
Synonyms HMG box transcription factor 3, HMG box transcription factor 4, TCF 3, TCF 4, TCF3, TCF4, TCF7L1, TCF7L2, Transcription factor 7 like 1
Calculated Molecular Weight 63 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC058894
Gene Symbol TCF7L1
Gene ID (NCBI) 83439
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9HCS4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TCF7L1 is one of TCF/LEF transcription factors that are mediators of the Wnt signaling pathway and are antagonized by the TGF-beta signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It's necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. This antibody raised against 1-200aa of human TCF7L1 can also react with TCF7L2.