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验证数据展示

  • WB analysis using 67652-1-Ig (same clone as 67652-1-PBS)

    WB analysis using 67652-1-Ig (same clone as 67652-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67652-1-Ig (TCF7L1/TCF7L2 antibody) at dilution of 1:50000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67652-1-PBS in a different storage buffer formulation.

TCF7L1/TCF7L2 Monoclonal antibody, PBS Only

TCF7L1/TCF7L2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67652-1-PBS

产品说明书

CloneNo. 2B2D12

宿主/亚型

Mouse / IgG2b

种属反应性

Human, Mouse

应用

WB, Indirect ELISA

别名

HMG box transcription factor 3, HMG box transcription factor 4, TCF 3, TCF 4, TCF3, TCF4, TCF7L1, TCF7L2, Transcription factor 7 like 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67652-1-PBS targets TCF7L1/TCF7L2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, Mouse
免疫原 TCF7L1/TCF7L2 fusion protein Ag28954 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 transcription factor 7-like 1 (T-cell specific, HMG-box)
别名 HMG box transcription factor 3, HMG box transcription factor 4, TCF 3, TCF 4, TCF3, TCF4, TCF7L1, TCF7L2, Transcription factor 7 like 1
计算分子量 63 kDa
观测分子量 70 kDa
GenBank蛋白编号BC058894
基因名称 TCF7L1
Gene ID (NCBI) 83439
RRIDAB_2882851
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9HCS4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TCF7L1 is one of TCF/LEF transcription factors that are mediators of the Wnt signaling pathway and are antagonized by the TGF-beta signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It's necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. This antibody raised against 1-200aa of human TCF7L1 can also react with TCF7L2.