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验证数据展示

  • WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

    WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

TERF1 Monoclonal antibody, PBS Only

TERF1 Monoclonal Antibody for Indirect ELISA, WB
Cat No. 67592-1-PBS

产品说明书

CloneNo. 1D10G4

宿主/亚型

Mouse / IgG1

种属反应性

rat, mouse, human

应用

Indirect ELISA, WB

别名

Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67592-1-PBS targets TERF1 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.

经测试应用 Indirect ELISA, WB Application Description
经测试反应性 rat, mouse, human
免疫原 TERF1 fusion protein Ag12540 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 telomeric repeat binding factor (NIMA-interacting) 1
别名 Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS
计算分子量 439 aa, 50 kDa
观测分子量 48-50 kDa
GenBank蛋白编号BC029378
基因名称 TERF1
Gene ID (NCBI) 7013
RRIDAB_2918494
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP54274
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.