TERF1 Monoclonal antibody, PBS Only

TERF1 Monoclonal Antibody for Indirect ELISA, WB

Host / Isotype

Mouse / IgG1

Reactivity

rat, mouse, human

Applications

Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

1D10G4

Cat no : 67592-1-PBS

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Synonyms

Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS



产品信息

67592-1-PBS targets TERF1 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.

Tested Applications Indirect ELISA, WB Application Description
Tested Reactivity rat, mouse, human
Immunogen TERF1 fusion protein Ag12540 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name telomeric repeat binding factor (NIMA-interacting) 1
Synonyms Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS
Calculated Molecular Weight 439 aa, 50 kDa
Observed Molecular Weight 48-50 kDa
GenBank Accession NumberBC029378
Gene Symbol TERF1
Gene ID (NCBI) 7013
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP54274
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.