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TEX14 Monoclonal antibody, PBS Only

TEX14 Monoclonal Antibody for WB, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat, rabbit

Applications

WB, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A11D6

Cat no : 67982-1-PBS

Print datasheet

Synonyms

SGK307, SGK307, Sugen kinase 307, testis expressed 14, Testis expressed protein 14, Testis expressed sequence 14, TEX14

验证数据展示

  • IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using TEX14 antibody (67982-1-Ig, Clone: 1A11D6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67982-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using TEX14 antibody (67982-1-Ig, Clone: 1A11D6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67982-1-PBS in a different storage buffer formulation.

  • WB analysis of rat testis using 67982-1-Ig (same clone as 67982-1-PBS)

    WB analysis of rat testis using 67982-1-Ig (same clone as 67982-1-PBS)

    rat testis tissue were subjected to SDS PAGE followed by western blot with 67982-1-Ig (TEX14 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67982-1-PBS in a different storage buffer formulation.

产品信息

67982-1-PBS targets TEX14 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.

Tested Applications WB, IF-P, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, rabbit
Immunogen TEX14 fusion protein Ag13143 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name testis expressed 14
Synonyms SGK307, SGK307, Sugen kinase 307, testis expressed 14, Testis expressed protein 14, Testis expressed sequence 14, TEX14
Calculated Molecular Weight957aa,107 kDa; 1497aa,168 kDa
Observed Molecular Weight180 kDa
GenBank Accession NumberBC040526
Gene Symbol TEX14
Gene ID (NCBI) 56155
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8IWB6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tex14 is required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Tex14 acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges.Tex14 also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment.