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验证数据展示

  • IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using TEX14 antibody (67982-1-Ig, Clone: 1A11D6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67982-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    IF Staining of mouse testis using 67982-1-Ig (same clone as 67982-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using TEX14 antibody (67982-1-Ig, Clone: 1A11D6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67982-1-PBS in a different storage buffer formulation.

  • WB analysis of rat testis using 67982-1-Ig (same clone as 67982-1-PBS)

    WB analysis of rat testis using 67982-1-Ig (same clone as 67982-1-PBS)

    rat testis tissue were subjected to SDS PAGE followed by western blot with 67982-1-Ig (TEX14 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67982-1-PBS in a different storage buffer formulation.

TEX14 Monoclonal antibody, PBS Only

TEX14 Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 67982-1-PBS

产品说明书

CloneNo. 1A11D6

宿主/亚型

Mouse / IgG2a

种属反应性

Human, mouse, rat, rabbit

应用

WB, IF-P, Indirect ELISA

别名

SGK307, SGK307, Sugen kinase 307, testis expressed 14, Testis expressed protein 14, Testis expressed sequence 14, TEX14

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67982-1-PBS targets TEX14 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat, rabbit
免疫原 TEX14 fusion protein Ag13143 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 testis expressed 14
别名 SGK307, SGK307, Sugen kinase 307, testis expressed 14, Testis expressed protein 14, Testis expressed sequence 14, TEX14
计算分子量957aa,107 kDa; 1497aa,168 kDa
观测分子量180 kDa
GenBank蛋白编号BC040526
基因名称 TEX14
Gene ID (NCBI) 56155
RRIDAB_2918731
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ8IWB6
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tex14 is required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Tex14 acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges.Tex14 also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment.