验证数据展示
产品信息
29324-1-PBS targets TFEC in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | TFEC fusion protein Ag30973 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | transcription factor EC |
别名 | |
计算分子量 | 347 aa, 39 kDa |
观测分子量 | 37-50 kDa |
GenBank蛋白编号 | BC029891 |
基因名称 | TFEC |
Gene ID (NCBI) | 22797 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O14948 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. The expression of TFEC is mainly in fibroblasts, myoblasts, chondrosarcoma cells and myeloma cells. 50kDa human TFEC isoforms are produced by alternative splicing (PMID: 29303964, PMID: 11467950).