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验证数据展示

  • WB analysis of human kidney using 60007-1-Ig (same clone as 60007-1-PBS)

    WB analysis of human kidney using 60007-1-Ig (same clone as 60007-1-PBS)

    human kidney tissue were subjected to SDS PAGE followed by western blot with 60007-1-Ig (TGFBI / BIGH3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60007-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon using 60007-1-Ig (same clone as 60007-1-PBS)

    IHC staining of human colon using 60007-1-Ig (same clone as 60007-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 60007-1-Ig (TGFBI / BIGH3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60007-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TGFBI antibody included
  • IHC staining of human colon using 60007-1-Ig (same clone as 60007-1-PBS)

    IHC staining of human colon using 60007-1-Ig (same clone as 60007-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 60007-1-Ig (TGFBI / BIGH3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60007-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TGFBI antibody included
  • IP experiment of HeLa using 60007-1-Ig (same clone as 60007-1-PBS)

    IP experiment of HeLa using 60007-1-Ig (same clone as 60007-1-PBS)

    IP result of anti-TGFBI / BIGH3 (IP:60007-1-Ig, 4ug; Detection:60007-1-Ig 1:300) with HeLa cells lysate 1200ug. This data was developed using the same antibody clone with 60007-1-PBS in a different storage buffer formulation.

  • IF Staining of human colon cancer using 60007-1-Ig (same clone as 60007-1-PBS)

    IF Staining of human colon cancer using 60007-1-Ig (same clone as 60007-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human colon cancer tissue using TGFBI / BIGH3 antibody (60007-1-Ig, Clone: 3E11D11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60007-1-PBS in a different storage buffer formulation.

  • IF Staining of human colon cancer using 60007-1-Ig (same clone as 60007-1-PBS)

    IF Staining of human colon cancer using 60007-1-Ig (same clone as 60007-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human colon cancer tissue using TGFBI / BIGH3 antibody (60007-1-Ig, Clone: 3E11D11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60007-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TGFBI / BIGH3 Monoclonal antibody, PBS Only

TGFBI / BIGH3 Monoclonal Antibody for WB, IHC, IF-P, IP, Indirect ELISA
Cat No. 60007-1-PBS

产品说明书

CloneNo. 3E11D11

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

WB, IHC, IF-P, IP, Indirect ELISA

别名

Beta ig h3, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, Kerato epithelin, LCD1, RGD CAP, TGFBI, TGFBI / BIGH3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TGFBI Ready-To-Use IHC Kit. TGFBI primary antibody included.

产品信息

60007-1-PBS targets TGFBI / BIGH3 in WB, IHC, IF-P, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF-P, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 TGFBI / BIGH3 fusion protein Ag0241 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 transforming growth factor, beta-induced, 68kDa
别名 Beta ig h3, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, Kerato epithelin, LCD1, RGD CAP, TGFBI, TGFBI / BIGH3
计算分子量 683 aa, 75 kDa
观测分子量 68 kDa
GenBank蛋白编号BC000097
基因名称 TGFBI
Gene ID (NCBI) 7045
ENSEMBL Gene IDENSG00000120708
RRIDAB_10896828
偶联类型 Unconjugated
形式 Liquid
纯化方式Caprylic acid/ammonium sulfate precipitation
UNIPROT IDQ15582
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TGFBI, also named as BIGH3, Kerato-epithelin and RGD-CAP, binds to type I, II, and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage, it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein, it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy, and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy.(PMID:20509890) Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD).