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TGFBR2 Monoclonal antibody, PBS Only

TGFBR2 Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse , Rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

2D5H7

Cat no : 66636-1-PBS

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Synonyms

AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TbetaR II, TGF beta receptor type 2, TGF beta receptor type II, TGF beta type II receptor, TGFbeta RII, TGFBR2, TGFR 2



产品信息

66636-1-PBS targets TGFBR2 in WB, IHC, ELISA applications and shows reactivity with Human, Mouse , Rat samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity Human, Mouse , Rat
Immunogen TGFBR2 fusion protein Ag25773 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name transforming growth factor, beta receptor II (70/80kDa)
Synonyms AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TbetaR II, TGF beta receptor type 2, TGF beta receptor type II, TGF beta type II receptor, TGFbeta RII, TGFBR2, TGFR 2
Calculated Molecular Weight 65 kDa
Observed Molecular Weight 65-80 kDa
GenBank Accession NumberBC040499
Gene Symbol TGFBR2
Gene ID (NCBI) 7048
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP37173
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TGF beta Receptor II (TGFBR2) is a member of the transforming growth factor-β (TGF-β) superfamily, which are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis (PMID: 10974075). TGFBR2 result in both SMAD4-dependent constraint of proliferation and SMAD4-independent activation of apoptosis (PMID: 29396446). It has some isoforms with the molecular weight of 70-80 kDa and ~90 kDa after glycosylated.