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Host
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验证数据展示

  • WB analysis using 66636-1-Ig (same clone as 66636-1-PBS)

    WB analysis using 66636-1-Ig (same clone as 66636-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66636-1-Ig (TGFBR2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 66636-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293T using 66636-1-Ig (same clone as 66636-1-PBS)

    WB analysis of HEK-293T using 66636-1-Ig (same clone as 66636-1-PBS)

    WB result of TGFBR2 antibody (66636-1-Ig; 1:30000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TGFBR2 transfected HEK-293T cells. This data was developed using the same antibody clone with 66636-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66636-1-Ig (same clone as 66636-1-PBS)

    IHC staining of human breast cancer using 66636-1-Ig (same clone as 66636-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66636-1-Ig (TGFBR2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66636-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66636-1-Ig (same clone as 66636-1-PBS)

    IHC staining of human breast cancer using 66636-1-Ig (same clone as 66636-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66636-1-Ig (TGFBR2 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66636-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TGFBR2 Monoclonal antibody, PBS Only

TGFBR2 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66636-1-PBS

产品说明书

CloneNo. 2D5H7

宿主/亚型

Mouse / IgG1

种属反应性

Human, Mouse , Rat

应用

WB, IHC, ELISA

别名

AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TbetaR II, TGF beta receptor type 2, TGF beta receptor type II, TGF beta type II receptor, TGFbeta RII, TGFBR2, TGFR 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66636-1-PBS targets TGFBR2 in WB, IHC, ELISA applications and shows reactivity with Human, Mouse , Rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 Human, Mouse , Rat
免疫原 TGFBR2 fusion protein Ag25773 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 transforming growth factor, beta receptor II (70/80kDa)
别名 AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TbetaR II, TGF beta receptor type 2, TGF beta receptor type II, TGF beta type II receptor, TGFbeta RII, TGFBR2, TGFR 2
计算分子量 65 kDa
观测分子量 65-80 kDa
GenBank蛋白编号BC040499
基因名称 TGFBR2
Gene ID (NCBI) 7048
RRIDAB_2881995
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP37173
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TGF beta Receptor II (TGFBR2) is a member of the transforming growth factor-β (TGF-β) superfamily, which are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis (PMID: 10974075). TGFBR2 result in both SMAD4-dependent constraint of proliferation and SMAD4-independent activation of apoptosis (PMID: 29396446). It has some isoforms with the molecular weight of 70-80 kDa and ~90 kDa after glycosylated.