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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67831-1-Ig (same clone as 67831-1-PBS)

    WB analysis using 67831-1-Ig (same clone as 67831-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67831-1-Ig (Thrombomodulin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 67831-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 67831-1-Ig (same clone as 67831-1-PBS)

    IHC staining of human lung cancer using 67831-1-Ig (same clone as 67831-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67831-1-Ig (Thrombomodulin antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67831-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD141/Thrombomodulin antibody included
  • IHC staining of human lung cancer using 67831-1-Ig (same clone as 67831-1-PBS)

    IHC staining of human lung cancer using 67831-1-Ig (same clone as 67831-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67831-1-Ig (Thrombomodulin antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67831-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD141/Thrombomodulin antibody included
  • IHC staining of human tonsillitis using 67831-1-Ig (same clone as 67831-1-PBS)

    IHC staining of human tonsillitis using 67831-1-Ig (same clone as 67831-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67831-1-Ig (CD141/Thrombomodulin antibody) at dilution of 1:5000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67831-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD141/Thrombomodulin antibody included

CD141/Thrombomodulin Monoclonal antibody, PBS Only

CD141/Thrombomodulin Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67831-1-PBS

产品说明书

CloneNo. 5A4C5

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

THBD, Thrombomodulin, THRM, Fetomodulin, CD141

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CD141/Thrombomodulin Ready-To-Use IHC Kit. CD141/Thrombomodulin primary antibody included.

产品信息

67831-1-PBS targets CD141/Thrombomodulin in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD141/Thrombomodulin fusion protein Ag5723 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 thrombomodulin
别名 THBD, Thrombomodulin, THRM, Fetomodulin, CD141
计算分子量 60 kDa
观测分子量105 kDa
GenBank蛋白编号BC035602
基因名称 THBD
Gene ID (NCBI) 7056
RRIDAB_2918593
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP07204
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Thrombomodulin, also known as THBD and CD141, is an endothelial cell surface glycoprotein that forms a 1:1 complex with the coagulation factor thrombin and plays an important role as a natural anticoagulant. Thrombomodulin serves to convert thrombin from a procoagulant protein into the activator for protein C. Once converted to activated protein C (APC), this protein serves as a major anticoagulant in blood (PMID: 2827310). Thrombomodulin is also located in other cells (keratinocytes, osteoblasts, macrophages,...) where it might be involved in cell differentiation or in inflammation (PMID: 9814688). In humans, thrombomodulin is encoded by the THBD gene. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. Thrombomodulin is glycosylated and has an apparent molecular weight of 75 to 110 kDa (PMID: 1650405; 2827310).