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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis of HEK-293 using 66083-1-Ig (same clone as 66083-1-PBS)

    WB analysis of HEK-293 using 66083-1-Ig (same clone as 66083-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 66083-1-Ig (TLE3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66083-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66083-1-Ig (same clone as 66083-1-PBS)

    IHC staining of human breast cancer using 66083-1-Ig (same clone as 66083-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 66083-1-Ig (TLE3 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 66083-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TLE3 antibody included
  • IP experiment of HEK-293 using 66083-1-Ig (same clone as 66083-1-PBS)

    IP experiment of HEK-293 using 66083-1-Ig (same clone as 66083-1-PBS)

    IP result of anti-TLE3 (IP:66083-1-Ig, 5ug; Detection:66083-1-Ig 1:500) with HEK-293 cells lysate 1480ug. This data was developed using the same antibody clone with 66083-1-PBS in a different storage buffer formulation.

TLE3 Monoclonal antibody, PBS Only

TLE3 Monoclonal Antibody for WB, IP, IHC, Indirect ELISA
Cat No. 66083-1-PBS

产品说明书

CloneNo. 1D11A8

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IP, IHC, Indirect ELISA

别名

ESG, ESG3, GRG3, HsT18976, KIAA1547, TLE3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TLE3 Ready-To-Use IHC Kit. TLE3 primary antibody included.

产品信息

66083-1-PBS targets TLE3 in WB, IP, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 TLE3 fusion protein Ag17906 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
别名 ESG, ESG3, GRG3, HsT18976, KIAA1547, TLE3
计算分子量 772 aa, 83 kDa
观测分子量 90 kDa
GenBank蛋白编号BC015729
基因名称 TLE3
Gene ID (NCBI) 7090
RRIDAB_11182267
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ04726
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TLE3, also named as KIAA1547 and ESG3, belongs to the WD repeat Groucho/TLE family. It is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE3 is a member of the transducin-like enhancer of split (TLE) family of proteins that have been implicated in the tumorgenesis and classification of sarcomas. It is a candidate biomarker of response to taxane therapy.(PMID:19309506 )