FcZero-rAb™ PE Anti-Human TLR3/CD283 Rabbit Recombinant Antibody

TLR3/CD283 FcZero-rAbTM Recombinant Antibody for FC (Intra)
Cat No. PE-FcA98016

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CloneNo. 230445F1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

TLR3, Toll-like receptor 3, toll like receptor 3, CD283, 230445F1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  PE
Size: 

-/ -


经过测试的应用

Positive FC (Intra) detected inhuman monocyte-derived immature dendritic cells

推荐稀释比

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-FcA98016 targets TLR3/CD283 in FC (Intra) applications and shows reactivity with human samples.

Tested Applications FC (Intra) Application Description
Tested Reactivity human
Immunogen TLR3/CD283 fusion protein Ag34044 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name toll-like receptor 3
Synonyms TLR3, Toll-like receptor 3, toll like receptor 3, CD283, 230445F1
Calculated Molecular Weight 904 aa, 104 kDa
GenBank Accession NumberBC094737
Gene Symbol TLR3
Gene ID (NCBI) 7098
Conjugate PE Fluorescent Dye
Excitation/Emission Maxima Wavelengths496 nm, 565 nm / 578 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

TLR3 belongs to the Toll-like receptor family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA. Upon recognition of dsRNA, TLR3 transmits signals via the adaptor protein TICAM-1/TRIF, leading to the induction of type I IFN, cytokine/chemokine production, and dendritic cell (DC) maturation (PMID: 18262679).

实验方案

Product Specific Protocols
FC protocol for PE TLR3/CD283 antibody PE-FcA98016Download protocol
Standard Protocols
Click here to view our Standard Protocols
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