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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 80165-1-RR (same clone as 80165-1-PBS)

    WB analysis using 80165-1-RR (same clone as 80165-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 80165-1-RR (TMEM173/STING antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 80165-1-RR (same clone as 80165-1-PBS)

    IP experiment of HeLa using 80165-1-RR (same clone as 80165-1-PBS)

    IP result of anti-TMEM173/STING (IP: 80165-1-RR, 4ug; Detection: 80165-1-RR 1:8000) with HeLa cells lysate 1800 ug. This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 80165-1-RR (TMEM173/STING antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with STING antibody included
  • IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 80165-1-RR (TMEM173/STING antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with STING antibody included
  • IF Staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    IF Staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using TMEM173/STING antibody (80165-1-RR, Clone: 7K7 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

  • IF Staining of THP-1 using 80165-1-RR (same clone as 80165-1-PBS)

    IF Staining of THP-1 using 80165-1-RR (same clone as 80165-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using TMEM173/STING antibody (80165-1-RR, Clone: 7K7 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 80165-1-RR

    Affinity and Kinetic Characterization of 80165-1-RR

    Biolayer interferometry (BLl) kinetic assays of 80165-1-RR against Human TMEM173/STING were performed. The affinity constant is 0.776 nM.

TMEM173/STING Recombinant antibody, PBS Only

TMEM173/STING Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA
Cat No. 80165-1-PBS

产品说明书

CloneNo. 7K7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA

别名

STING, NET23, MPYS, MITA, ERIS

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy STING Ready-To-Use IHC Kit. STING primary antibody included.

产品信息

80165-1-PBS targets TMEM173/STING in WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IF-P, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TMEM173/STING fusion protein Ag13921 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transmembrane protein 173
别名 STING, NET23, MPYS, MITA, ERIS
计算分子量 379 aa, 42 kDa
观测分子量37 kDa
GenBank蛋白编号BC047779
基因名称 STING
Gene ID (NCBI) 340061
RRIDAB_2918870
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ86WV6
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.