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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

TMEM184B Polyclonal antibody, PBS Only

TMEM184B Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 28031-1-PBS

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

28031-1-PBS targets TMEM184B in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen TMEM184B fusion protein Ag27704 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transmembrane protein 184B
Synonyms
GenBank Accession NumberBC015489
Gene Symbol TMEM184B
Gene ID (NCBI) 25829
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y519
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transmembrane protein 184B (TMEM184B) is a seven-pass transmembrane protein highly expressed in the nervous system and is thought to play a role in neuronal excitability, synaptic structure, and expression of key developmental and adult pathways involved in neuronal differentiation (PMID: 27122027; 37730546). TMEM184B may activate the MAP kinase signaling pathway (PMID: 12761501). TMEM184B has also been reported to be necessary for interleukin-31-induced itch, promoting adult somatosensation through developmental Wnt signaling and promotion of proper pruriceptive gene expression (PMID: 34629389).