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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84510-4-RR (same clone as 84510-4-PBS)

    WB analysis using 84510-4-RR (same clone as 84510-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84510-4-RR (TMEM41B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84510-4-PBS in a different storage buffer formulation.

TMEM41B Recombinant antibody, PBS Only

TMEM41B Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84510-4-PBS
CloneNo. 242017C11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Transmembrane protein 41B, KIAA0033, 242017C11

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TMEM41B Ready-To-Use IHC Kit. TMEM41B primary antibody included.

产品信息

84510-4-PBS targets TMEM41B in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen TMEM41B fusion protein Ag30810 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name transmembrane protein 41B
Synonyms Transmembrane protein 41B, KIAA0033, 242017C11
Calculated Molecular Weight32 kDa
Observed Molecular Weight25-28 kDa
GenBank Accession NumberBC035034
Gene Symbol TMEM41B
Gene ID (NCBI) 440026
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ5BJD5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.