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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84510-4-RR (same clone as 84510-4-PBS)

    WB analysis using 84510-4-RR (same clone as 84510-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84510-4-RR (TMEM41B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84510-4-PBS in a different storage buffer formulation.

TMEM41B Recombinant antibody, PBS Only

TMEM41B Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84510-4-PBS

产品说明书

CloneNo. 242017C11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

Transmembrane protein 41B, KIAA0033, 242017C11

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TMEM41B Ready-To-Use IHC Kit. TMEM41B primary antibody included.

产品信息

84510-4-PBS targets TMEM41B in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 TMEM41B fusion protein Ag30810 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transmembrane protein 41B
别名 Transmembrane protein 41B, KIAA0033, 242017C11
计算分子量32 kDa
观测分子量25-28 kDa
GenBank蛋白编号BC035034
基因名称 TMEM41B
Gene ID (NCBI) 440026
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ5BJD5
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.