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TMEM63B Polyclonal antibody

TMEM63B Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 24226-1-AP

Print datasheet

Synonyms

Transmembrane protein 63B, CSC1-like protein 2, C6orf110

验证数据展示

  • WB analysis using 24226-1-AP

    WB analysis using 24226-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 24226-1-AP (TMEM63B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24226-1-AP targets TMEM63B in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Immunogen TMEM63B fusion protein Ag21573 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transmembrane protein 63B
Synonyms Transmembrane protein 63B, CSC1-like protein 2, C6orf110
Calculated Molecular Weight 832 aa, 95 kDa
Observed Molecular Weight95 kDa
GenBank Accession NumberBC136769
Gene Symbol TMEM63B
Gene ID (NCBI) 55362
RRIDAB_3085727
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ5T3F8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TMEM63B, also known as C6orf110, belongs to the TMEM63 family. TMEM63B is a mechanosensitive cation channel activated by hypoosmotic stress and mechanic stimulation. Genetic deletion of TMEM63B is a cause of necroptosis of outer hair cells (OHCs) and progressive hearing loss (PMID: 32375046).

实验方案

Product Specific Protocols
WB protocol for TMEM63B antibody 24226-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols