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TMEM63B Polyclonal antibody

TMEM63B Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 24226-1-AP

Print datasheet

Synonyms

Transmembrane protein 63B, CSC1-like protein 2, C6orf110

验证数据展示

  • WB analysis using 24226-1-AP

    WB analysis using 24226-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 24226-1-AP (TMEM63B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24226-1-AP targets TMEM63B in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Immunogen TMEM63B fusion protein Ag21573 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transmembrane protein 63B
Synonyms Transmembrane protein 63B, CSC1-like protein 2, C6orf110
Calculated Molecular Weight 832 aa, 95 kDa
Observed Molecular Weight95 kDa
GenBank Accession NumberBC136769
Gene Symbol TMEM63B
Gene ID (NCBI) 55362
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ5T3F8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TMEM63B, also known as C6orf110, belongs to the TMEM63 family. TMEM63B is a mechanosensitive cation channel activated by hypoosmotic stress and mechanic stimulation. Genetic deletion of TMEM63B is a cause of necroptosis of outer hair cells (OHCs) and progressive hearing loss (PMID: 32375046).

实验方案

Product Specific Protocols
WB protocol for TMEM63B antibody 24226-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols