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Anti-Human TNF beta Rabbit Recombinant Antibody, PBS Only

TNF beta Uni-rAbTM Recombinant Antibody for FC (Intra)

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

Conjugate

Unconjugated

CloneNo.

240393C3

Cat no : 98056-1-PBS

Print datasheet

Synonyms

LTA, TNF β, Lymphotoxin-alpha, Lymphotoxin alpha, LT alpha

验证数据展示

  • FC experiment of human PBMCs using 98056-1-RR (same clone as 98056-1-PBS)

    FC experiment of human PBMCs using 98056-1-RR (same clone as 98056-1-PBS)

    1x10^6 untreated or anti-CD3/CD28 treated human PBMCs were intracellularly stained with 0.25 ug Anti-Human TNFB Rabbit Recombinant Antibody (98056-1-RR, Clone: 240393C3) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98056-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98056-1-RR

    Affinity and Kinetic Characterization of 98056-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98056-1-RR against Human TNF Beta were performed. The affinity constant is below 1 pM.

产品信息

The immunogen of 98056-1-PBS is TNF beta Fusion Protein expressed in E. coli.

Tested Applications FC (Intra) Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name lymphotoxin alpha (TNF superfamily, member 1)
Synonyms LTA, TNF β, Lymphotoxin-alpha, Lymphotoxin alpha, LT alpha
Calculated Molecular Weight 205 aa, 22 kDa
GenBank Accession NumberBC034729
Gene Symbol TNF beta
Gene ID (NCBI) 4049
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP01374
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TNF beta also known as lymphotoxin alpha (LTA), is a member of the tumor necrosis factor family, and is a cytokine produced by lymphocytes. TNF Beta is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. TNF Beta also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.