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Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody

TNFRSF13B/CD267 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241317D8

Cat no : 98100-1-RR

Print datasheet

Synonyms

CD267, TNFRSF13B, TACI, CVID, 241317D8

验证数据展示

  • FC experiment of human PBMCs using 98100-1-RR

    FC experiment of human PBMCs using 98100-1-RR

    1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7) and 0.25 ug Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody (98100-1-RR, Clone:241317D8) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), or Isotype Control. Cells were not fixed.

  • FC experiment of human PBMCs using 98100-1-RR

    FC experiment of human PBMCs using 98100-1-RR

    1x10^6 human PBMCs were stained with 0.25 ug Anti-Human TNFRSF13B/CD267 Rabbit Recombinant Antibody (98100-1-RR, Clone:241317D8)(red)and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), or Isotype Control(blue). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98100-1-RR

    Affinity and Kinetic Characterization of 98100-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98100-1-RR against Human TNFRSF13B/CD267 were performed. The affinity constant is 4.18 nM.

经过测试的应用

Positive FC detected inhuman PBMCs

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98100-1-RR targets TNFRSF13B/CD267 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name tumor necrosis factor receptor superfamily, member 13B
Synonyms CD267, TNFRSF13B, TACI, CVID, 241317D8
Calculated Molecular Weight 293 aa, 32 kDa
GenBank Accession NumberBC109392
Gene Symbol TNFRSF13B/CD267
Gene ID (NCBI) 23495
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO14836
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

实验方案

Product Specific Protocols
FC protocol for TNFRSF13B/CD267 antibody 98100-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols