验证数据展示
产品信息
67829-1-PBS targets TOE1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | TOE1 fusion protein Ag28982 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | target of EGR1, member 1 (nuclear) |
别名 | FLJ13949, Target of EGR1 protein 1, TOE1 |
计算分子量 | 510 aa, 57 kDa |
观测分子量 | 57 kDa |
GenBank蛋白编号 | BC009364 |
基因名称 | TOE1 |
Gene ID (NCBI) | 114034 |
RRID | AB_2918591 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q96GM8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TOE1, also known as hCaf1z, belongs to the DEDD family of deadenylases. TOE1 was initially identified as a direct target gene of ERG1, an immediate early transcription factor. TOE1 encodes an Asp-Glu-Asp-Asp deadenylase that specifically localizes to Cajal bodies in the nucleus, where assembly and maturation of small nuclear ribonucleoprotein particles, and telomerase ribonucleoprotein complex take place (PMID: 36257135). TOE1 has 2 isoforms with the molecular mass of 48 and 57 kDa.