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TOX2 Polyclonal antibody, PBS Only

TOX2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 30474-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 30474-1-AP (same clone as 30474-1-PBS)

    WB analysis using 30474-1-AP (same clone as 30474-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30474-1-AP (TOX2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30474-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 30474-1-AP (same clone as 30474-1-PBS)

    IF Staining of A431 using 30474-1-AP (same clone as 30474-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using TOX2 antibody (30474-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 30474-1-PBS in a different storage buffer formulation.

产品信息

30474-1-PBS targets TOX2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen TOX2 fusion protein Ag31226 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name TOX high mobility group box family member 2
Synonyms
Calculated Molecular Weight 488 aa, 52 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC007636
Gene Symbol TOX2
Gene ID (NCBI) 84969
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96NM4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TOX2 is a transcription factor belonging to the TOX (thymocyte selection-associated HMG box) family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. A previous study showed that TOX2 is preferentially expressed in human NK cells among various leukocyte populations and is required for in vitro and in vivo human NK cell differentiation from UCB-derived CD341 hematopoietic stem cells (HSCs) (PMID: 25352127).