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TRIM26 Recombinant antibody, PBS Only

TRIM26 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242154B5

Cat no : 84661-4-PBS

Print datasheet

Synonyms

ZNF173, Tripartite motif-containing protein 26, TRIM, RNF95, EC:2.3.2.27

验证数据展示

  • WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84661-4-RR (TRIM26 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy TRIM26 Ready-To-Use IHC Kit. TRIM26 primary antibody included.

产品信息

84661-4-PBS targets TRIM26 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen TRIM26 fusion protein Ag25546 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name tripartite motif-containing 26
Synonyms ZNF173, Tripartite motif-containing protein 26, TRIM, RNF95, EC:2.3.2.27
Calculated Molecular Weight 62 kDa
Observed Molecular Weight 60-70 kDa
GenBank Accession NumberBC024039
Gene Symbol TRIM26
Gene ID (NCBI) 7726
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ12899
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation. (PMID: 25763818, PMID: 26611359)