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TRIM26 Recombinant antibody

TRIM26 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

242154B5

Cat no : 84661-4-RR

Print datasheet

Synonyms

ZNF173, Tripartite motif-containing protein 26, TRIM, RNF95, EC:2.3.2.27

验证数据展示

  • WB analysis using 84661-4-RR

    WB analysis using 84661-4-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 84661-4-RR (TRIM26 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inHeLa cells, HepG2 cells, Jurkat cells, HEK-293T cells
Planning an IHC experiment? We recommend our IHCeasy TRIM26 Ready-To-Use IHC Kit. TRIM26 primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84661-4-RR targets TRIM26 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen TRIM26 fusion protein Ag25546 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name tripartite motif-containing 26
Synonyms ZNF173, Tripartite motif-containing protein 26, TRIM, RNF95, EC:2.3.2.27
Calculated Molecular Weight 62 kDa
Observed Molecular Weight 60-70 kDa
GenBank Accession NumberBC024039
Gene Symbol TRIM26
Gene ID (NCBI) 7726
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ12899
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation. (PMID: 25763818, PMID: 26611359)

实验方案

Product Specific Protocols
WB protocol for TRIM26 antibody 84661-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols