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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of HeLa using 67149-1-Ig (same clone as 67149-1-PBS)

    WB analysis of HeLa using 67149-1-Ig (same clone as 67149-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67149-1-Ig (TROVE2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67149-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67149-1-Ig (same clone as 67149-1-PBS)

    IHC staining of mouse brain using 67149-1-Ig (same clone as 67149-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67149-1-Ig (TROVE2 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67149-1-PBS in a different storage buffer formulation.

TROVE2 Monoclonal antibody, PBS Only

TROVE2 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67149-1-PBS

产品说明书

CloneNo. 2A4E5

宿主/亚型

Mouse / IgG2a

种属反应性

Human, Mouse, Rat

应用

WB, IHC, Indirect ELISA

别名

60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, Ro 60 kDa autoantigen, RO60, RoRNP, Sjoegren syndrome antigen A2, SS A, SSA2, TROVE domain family member 2, TROVE domain family, member 2, TROVE2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67149-1-PBS targets TROVE2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human, Mouse, Rat
免疫原 TROVE2 fusion protein Ag4379 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 TROVE domain family, member 2
别名 60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, Ro 60 kDa autoantigen, RO60, RoRNP, Sjoegren syndrome antigen A2, SS A, SSA2, TROVE domain family member 2, TROVE domain family, member 2, TROVE2
计算分子量 60 kDa
观测分子量 60 kDa
GenBank蛋白编号BC036658
基因名称 TROVE2
Gene ID (NCBI) 6738
RRIDAB_2882447
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP10155
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TROVE2, also named as RO60 or RoRNP, is a 538 amino acid protein, which is localized in cytoplasmic mRNP granules containing untranslated mRNAs. TROVE2 as a RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. TROVE2 may stabilize some of these RNAs and protect them from degradation (PubMed:18056422). TROVE2 binds to endogenous Alu retroelements which are induced by type I IFN and stimulate porinflammaotry cytokine secretion.