TTBK2 Recombinant antibody, PBS Only
TTBK2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
241456B4
验证数据展示
产品信息
The immunogen of 84634-1-PBS is TTBK2 Fusion Protein expressed in E. coli.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | TTBK2 fusion protein Ag7108 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | tau tubulin kinase 2 |
| Synonyms | |
| Calculated Molecular Weight | 137 kDa |
| Observed Molecular Weight | 137-150 kDa |
| GenBank Accession Number | BC071556 |
| Gene Symbol | TTBK2 |
| Gene ID (NCBI) | 146057 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q6IQ55 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TTBK2(tau tubulin kinase 2) plays an important role in the tau cascade and in spinocerebellar degeneration. The N-terminus of TTBK2 has a serine-threonine-tyrosine kinase domain, and a C-terminal region shows homology to TTBK1. TTBK1 and TTBK2 function as regulators of TDP-43 phosphorylation. TTBK1/2 may be attractive drug targets for therapeutic interventions in TDP-43 proteinopathies such as FTLD-TDP and ALS.(PMID:25473830).