TTK Recombinant antibody, PBS Only

TTK Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84744-1-PBS

产品说明书

CloneNo. 241873B2

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy TTK Ready-To-Use IHC Kit. TTK primary antibody included.

产品信息

84744-1-PBS targets TTK in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TTK fusion protein Ag20556 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 TTK protein kinase
别名
计算分子量 97 kDa
观测分子量97 kDa
GenBank蛋白编号BC000633
基因名称 TTK
Gene ID (NCBI) 7272
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP33981
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Mps1 family of kinases colocalizes with mitotic checkpoint proteins in kinetochores and/or spindle pole bodies/centrosomes. TTK has been shown to be a cell cycle-regulated kinase displaying maximum activity during M phase(PMID:15618221). Its kinase activity is required for proper chromosome segregation during mitosis through its involvements in microtubule-chromosome attachment error correction and the mitotic checkpoint(PMID:20937696). TTK mRNA is present at relatively high levels in testis and thymus, tissues which contain a large number of proliferating cells, but is not detected in most other benign tissues (PMID:1639825). It has 2 isoforms produced by alternative splicing (PMID:25137017).

Loading...