TTK Recombinant antibody

TTK Recombinant Antibody for WB, ELISA
Cat No. 84744-1-RR

产品说明书

CloneNo. 241873B2

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHEK-293 cells, HeLa cells, DU 145 cells, MCF-7 cells
Planning an IHC experiment? We recommend our IHCeasy TTK Ready-To-Use IHC Kit. TTK primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84744-1-RR targets TTK in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TTK fusion protein Ag20556 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 TTK protein kinase
别名
计算分子量 97 kDa
观测分子量97 kDa
GenBank蛋白编号BC000633
基因名称 TTK
Gene ID (NCBI) 7272
RRIDAB_3672129
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP33981
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Mps1 family of kinases colocalizes with mitotic checkpoint proteins in kinetochores and/or spindle pole bodies/centrosomes. TTK has been shown to be a cell cycle-regulated kinase displaying maximum activity during M phase(PMID:15618221). Its kinase activity is required for proper chromosome segregation during mitosis through its involvements in microtubule-chromosome attachment error correction and the mitotic checkpoint(PMID:20937696). TTK mRNA is present at relatively high levels in testis and thymus, tissues which contain a large number of proliferating cells, but is not detected in most other benign tissues (PMID:1639825). It has 2 isoforms produced by alternative splicing (PMID:25137017).

实验方案

Product Specific Protocols
WB protocol for TTK antibody 84744-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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