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验证数据展示

  • WB analysis using 82763-5-RR (same clone as 82763-5-PBS)

    WB analysis using 82763-5-RR (same clone as 82763-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82763-5-RR (TTL antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82763-5-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 82763-5-RR (same clone as 82763-5-PBS)

    WB analysis of HeLa using 82763-5-RR (same clone as 82763-5-PBS)

    WB result of TTL antibody (82763-5-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TTL transfected HeLa cells. This data was developed using the same antibody clone with 82763-5-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TTL Recombinant antibody, PBS Only

TTL Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 82763-5-PBS

产品说明书

CloneNo. 3P9

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

Tubulin--tyrosine ligase, tubulin tyrosine ligase, Tubulin tyrosine ligase, EC:6.3.2.25, 3P9

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

82763-5-PBS targets TTL in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TTL fusion protein Ag4526 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tubulin tyrosine ligase
别名 Tubulin--tyrosine ligase, tubulin tyrosine ligase, Tubulin tyrosine ligase, EC:6.3.2.25, 3P9
计算分子量 377 aa, 43 kDa
观测分子量 43 kDa
GenBank蛋白编号BC036819
基因名称 TTL
Gene ID (NCBI) 150465
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ8NG68
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.