验证数据展示
产品信息
83870-1-PBS targets UCP1 in WB, IHC, IF-P, ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IF-P, ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | UCP1 fusion protein Ag20388 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | uncoupling protein 1 (mitochondrial, proton carrier) |
别名 | UCP 1, UCP, Thermogenin, SLC25A7, 240782F3 |
计算分子量 | 307 aa, 33 kDa |
观测分子量 | 33 kDa |
GenBank蛋白编号 | BC098168 |
基因名称 | UCP1 |
Gene ID (NCBI) | 7350 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | P25874 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
UCP-1 (Mitochondrial uncoupling protein 1), is a mitochondrial transporter protein that creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. It has been identified a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. UCP-1 expression is usually restricted to brown adipose when induced by cold exposure and thyroid hormone.