UGT8 Recombinant antibody
UGT8 Recombinant Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
230107A6
验证数据展示
产品信息
82874-1-RR targets UGT8 in ELISA applications and shows reactivity with Human samples.
| Tested Applications | ELISA Application Description |
| Tested Reactivity | Human |
| Immunogen | UGT8 fusion protein Ag13137 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | UDP glycosyltransferase 8 |
| Synonyms | Cerebroside synthase, CGT, UDP glycosyltransferase 8, UGT4, UGT8 |
| Calculated Molecular Weight | 541 aa, 61 kDa |
| GenBank Accession Number | BC075069 |
| Gene Symbol | UGT8 |
| Gene ID (NCBI) | 7368 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q16880 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
UGT8, also known as galacotosylceramide synthase or CGT (ceramide galactosyltransferase), is a key enzyme for galacotosylceramide (GalCer) biosynthesis. It is an ER transmembrane protein and has limited tissue distribution, with predominance in Schwann cells, oligodendrocytes, kidneys, testes, and intestine. UGT8 is highly enriched in myelin in the central nervous system. Its expression levels are strongly associated with histological typing in human oligodendrogliomas and astrocytomas; can be used as molecular marker to distinguish these tumors. Higher UGT8 levels had also been linked to metastatic properties of cancer cells.
