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Host
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Conjugate
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验证数据展示

  • WB analysis using 68483-1-Ig (same clone as 68483-1-PBS)

    WB analysis using 68483-1-Ig (same clone as 68483-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68483-1-Ig (UNC13A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68483-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 68483-1-Ig (same clone as 68483-1-PBS)

    IHC staining of mouse brain using 68483-1-Ig (same clone as 68483-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68483-1-Ig (UNC13A antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68483-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 68483-1-Ig (same clone as 68483-1-PBS)

    IHC staining of mouse brain using 68483-1-Ig (same clone as 68483-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68483-1-Ig (UNC13A antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68483-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 68483-1-Ig (same clone as 68483-1-PBS)

    IF Staining of SH-SY5Y using 68483-1-Ig (same clone as 68483-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using UNC13A antibody (68483-1-Ig, Clone: 3C3A9 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68483-1-PBS in a different storage buffer formulation.

UNC13A Monoclonal antibody, PBS Only

UNC13A Monoclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 68483-1-PBS

产品说明书

CloneNo. 3C3A9

宿主/亚型

Mouse / IgG2a

种属反应性

Human, mouse, rat, pig, rabbit

应用

WB, IHC, IF/ICC, ELISA

别名

KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A (C. elegans), UNC13A

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68483-1-PBS targets UNC13A in WB, IHC, IF/ICC, ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
经测试反应性 Human, mouse, rat, pig, rabbit
免疫原 Peptide 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 unc-13 homolog A (C. elegans)
别名 KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A (C. elegans), UNC13A
计算分子量 193 kDa
观测分子量193-210 kDa
GenBank蛋白编号NM_001080421
基因名称 UNC13A
Gene ID (NCBI) 23025
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9UPW8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

UNC13A, also named KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in INS secretion. The antibody is specific to UNC13A.