CoraLite® Plus 488-conjugated VASH2 Monoclonal antibody
VASH2 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
3A11D10
验证数据展示
经过测试的应用
| Positive IF/ICC detected in | SKOV-3 cells |
For other applications, we recommend the unconjugated version of this antibody, 67753-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-67753 targets VASH2 in IF/ICC applications and shows reactivity with Human samples.
| Tested Applications | IF/ICC Application Description |
| Tested Reactivity | Human |
| Immunogen | VASH2 fusion protein Ag29985 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | vasohibin 2 |
| Synonyms | FLJ12505, RP11 275G3.1, VASH2, VASHL, vasohibin 2, Vasohibin like protein |
| Calculated Molecular Weight | 355 aa, 40 kDa |
| Observed Molecular Weight | 34 kDa |
| GenBank Accession Number | BC028194 |
| Gene Symbol | VASH2 |
| Gene ID (NCBI) | 79805 |
| RRID | AB_2919537 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q86V25 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
VASH2, also named as vasohibin 2, is an important pro-angiogenesis factor in solid tumor. It has been reported that VASH2 is expressed in mononuclear cells mobilized from bone marrow to promote angiogenesis. VASH2 also plays a key role in axon formation. VASH2 is localized as a nuclear type(with 311 amino acid residues) and cytoplasmic type (with 355 amino acid residues and low abundance). Cytoplasmic VASH2 is associated with carcinoma angiogenesis, while nuclear VASH2 may be associated with cell proliferation. 67753-1-Ig antibody recognizes both the nuclear and cytoplasmic isoforms. (PMID:23615928; 19204325; 31235911; 26177649)
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 VASH2 antibody CL488-67753 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |