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验证数据展示

  • FC experiment of HUVEC using 98079-1-RR

    FC experiment of HUVEC using 98079-1-RR

    1x10^6 TNF- α treated HUVEC cells were surface stained with 0.25 ug Anti-Human VCAM-1/CD106 Rabbit Recombinant Antibody (98079-1-RR, Clone:241283G8)(red), or 0.25 ug Isotype Control (blue), or 1x10^6 untreated HUVEC cells were surface stained with 0.25 ug Anti-Human VCAM-1/CD106 Rabbit Recombinant Antibody (98079-1-RR, Clone:241283G8) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(black). Cells were not fixed.

  • FC experiment of HUVEC using 98079-1-RR

    FC experiment of HUVEC using 98079-1-RR

    1x10^6 TNF- α treated HUVEC cells were surface stained with 0.25 ug Anti-Human VCAM-1/CD106 Rabbit Recombinant Antibody (98079-1-RR, Clone:241283G8) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98079-1-RR

    Affinity and Kinetic Characterization of 98079-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98079-1-RR against Human VCAM-1/CD106 were performed. The affinity constant is 1.71 nM.

Anti-Human VCAM-1/CD106 Rabbit Recombinant Antibody

VCAM-1/CD106 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98079-1-RR

产品说明书

CloneNo. 241283G8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

VCAM1, VCAM-1, Soluble Vascular Cell Adhesion Molecule-1, L1CAM, INCAM-100

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive FC detected inTNF- α treated HUVEC cells
Planning an IHC experiment? We recommend our IHCeasy VCAM-1 Ready-To-Use IHC Kit. VCAM-1 primary antibody included.

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98079-1-RR targets VCAM-1/CD106 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 vascular cell adhesion molecule 1
别名 VCAM1, VCAM-1, Soluble Vascular Cell Adhesion Molecule-1, L1CAM, INCAM-100
计算分子量81 kDa
GenBank蛋白编号NM_001078.4
基因名称 VCAM-1
Gene ID (NCBI) 7412
RRIDAB_3672226
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP19320-1
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).

实验方案

Product Specific Protocols
FC protocol for VCAM-1/CD106 antibody 98079-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols