Anti-Human VEGFR2/CD309 Rabbit Recombinant Antibody

VEGFR2/CD309 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98009-1-RR

产品说明书

CloneNo. 230238B11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

KDR, VEGFR2, VEGFR2/KDR, Protein-tyrosine kinase receptor flk-1, FLK-1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
CoraLite®594
规格: 

-/ -


经过测试的应用

Positive FC detected inHUVEC cells

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98009-1-RR targets VEGFR2/CD309 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 kinase insert domain receptor (a type III receptor tyrosine kinase)
别名 KDR, VEGFR2, VEGFR2/KDR, Protein-tyrosine kinase receptor flk-1, FLK-1
计算分子量152kd
GenBank蛋白编号NM_002253
基因名称 KDR
Gene ID (NCBI) 3791
RRIDAB_3672151
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP35968-1
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

VEGFR2, also named as CD309, KDR and FLK1, is a receptor for VEGF or VEGFC. VEGFR2 which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGFR2 functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

实验方案

Product Specific Protocols
FC protocol for VEGFR2/CD309 antibody 98009-1-RRDownload protocol
Standard Protocols
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