CoraLite®594 Anti-Human VEGFR2/CD309 Rabbit Recombinant Antibody

VEGFR2/CD309 Uni-rAbTM Recombinant Antibody for FC
Cat No. CL594-98009

产品说明书

CloneNo. 230238B11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

KDR, VEGFR2, VEGFR2/KDR, Protein-tyrosine kinase receptor flk-1, FLK-1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -


经过测试的应用

Positive FC detected inHUVEC cells
For other applications, we recommend the unconjugated version of this antibody, 98009-1-PBS

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-98009 targets VEGFR2/CD309 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 kinase insert domain receptor (a type III receptor tyrosine kinase)
别名 KDR, VEGFR2, VEGFR2/KDR, Protein-tyrosine kinase receptor flk-1, FLK-1
计算分子量152kd
GenBank蛋白编号NM_002253
基因名称 KDR
Gene ID (NCBI) 3791
RRIDAB_3673534
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP35968-1
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

VEGFR2, also named as CD309, KDR and FLK1, is a receptor for VEGF or VEGFC. VEGFR2 which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGFR2 functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

实验方案

Product Specific Protocols
FC protocol for CL594 VEGFR2/CD309 antibody CL594-98009Download protocol
Standard Protocols
Click here to view our Standard Protocols
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