验证数据展示
产品信息
23566-1-PBS targets VSX1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | VSX1 fusion protein Ag19222 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | visual system homeobox 1 |
别名 | |
计算分子量 | 365 aa, 38 kDa |
观测分子量 | 70 kDa |
GenBank蛋白编号 | BC126228 |
基因名称 | VSX1 |
Gene ID (NCBI) | 30813 |
RRID | AB_2879297 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9NZR4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
VSX1(visual system homeobox 1) is a member of the Vsx1 group of vertebrate paired-like homeodomain transcription factors locating to the nucleus. Mutations in the VSX1 gene in keratoconus have been reported in many studies. VSX1 is considered important in ocular development and is particularly involved in the developing cornea (PMID:21139977). And previous studies have identified that Vsx1 participates in regulating retinal progenitor proliferation, differentiation and functional maintenance of bipolar cells (PMID:25150888). It was demonstrated that Vsx1 express in embryonic craniofacial, adult corneal, and adult retinal cDNA libraries.VSX1 mRNA has been found in the outer tier of the inner nuclear layer of the human retina and the cornea (PMID: 21139977).