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  • Featured Product
  • KD/KO Validated

WDR1 Monoclonal antibody, PBS Only

WDR1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2D11E1

Cat no : 67937-1-PBS

Print datasheet

Synonyms

WD repeat containing protein 1, NORI-1, NORI 1, AIP1, Actin-interacting protein 1

验证数据展示

  • WB analysis using 67937-1-Ig (same clone as 67937-1-PBS)

    WB analysis using 67937-1-Ig (same clone as 67937-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67937-1-Ig (WDR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67937-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 67937-1-Ig (same clone as 67937-1-PBS)

    WB analysis of HEK-293 using 67937-1-Ig (same clone as 67937-1-PBS)

    WB result of WDR1 antibody (67937-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-WDR1 transfected HEK-293 cells. This data was developed using the same antibody clone with 67937-1-PBS in a different storage buffer formulation.

产品信息

67937-1-PBS targets WDR1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, rat
Immunogen WDR1 fusion protein Ag30967 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name WD repeat domain 1
Synonyms WD repeat containing protein 1, NORI-1, NORI 1, AIP1, Actin-interacting protein 1
Calculated Molecular Weight 606 aa, 66 kDa
Observed Molecular Weight65-66 kDa
GenBank Accession NumberBC030541
Gene Symbol WDR1
Gene ID (NCBI) 9948
RRIDAB_2918689
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO75083
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WDR1, which belongs to the WD repeat AIP1 family, also known as AIP1, is a 606 amino acid protein that localizes to the cytoskeleton. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WDR1 induces the disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PMID:15629458, 27557945, 29751004). WDR1 mutations may impair the ability of WDR1 to regulate cofilin-mediated actin depolymerization, and are associated with periodic fever, immunodeficiency, and thrombocytopenia syndrome (PMID: 27557945,27994071,29751004).