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0
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0
Conjugate
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验证数据展示

  • IP experiment of HeLa using 22722-1-AP (same clone as 22722-1-PBS)

    IP experiment of HeLa using 22722-1-AP (same clone as 22722-1-PBS)

    IP result of anti-WHSC1 (IP:22722-1-AP, 3ug; Detection:22722-1-AP 1:300) with HeLa cells lysate 2000ug. This data was developed using the same antibody clone with 22722-1-PBS in a different storage buffer formulation.

  • WB analysis of HCT 116 using 22722-1-AP (same clone as 22722-1-PBS)

    WB analysis of HCT 116 using 22722-1-AP (same clone as 22722-1-PBS)

    HCT 116 cells were subjected to SDS PAGE followed by western blot with 22722-1-AP (WHSC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22722-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 22722-1-AP (same clone as 22722-1-PBS)

    IHC staining of human breast cancer using 22722-1-AP (same clone as 22722-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 22722-1-AP (WHSC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22722-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 22722-1-AP (same clone as 22722-1-PBS)

    IHC staining of human breast cancer using 22722-1-AP (same clone as 22722-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 22722-1-AP (WHSC1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22722-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 22722-1-AP (same clone as 22722-1-PBS)

    IHC staining of human breast cancer using 22722-1-AP (same clone as 22722-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 22722-1-AP (WHSC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22722-1-PBS in a different storage buffer formulation.

WHSC1 Polyclonal antibody, PBS Only

WHSC1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 22722-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

22722-1-PBS targets WHSC1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 WHSC1 fusion protein Ag18611 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Wolf-Hirschhorn syndrome candidate 1
别名
计算分子量 162 kDa
观测分子量 70 kDa, 150 kDa
GenBank蛋白编号BC152412
基因名称 WHSC1
Gene ID (NCBI) 7468
RRIDAB_2879156
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen Affinity purified
UNIPROT IDO96028
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WHSC1 (also known as MMSET or NSD2) is a SET domain containing histone lysine methyltransferase that can di- and trimethylate histone H3 at lysine 36 (H3K36). WHSC1 mRNA is highly expressed in embryonic tissues, especially those with high degrees of proliferation, whereas in adult tissues,the mRNA is primarily expressed in thymus and testis. WHSC1 is implicated in cellular adhesion, clonogenic growth and tumorigenicity. Its overexpression has been found in various cancers. It undergoes alternative splicing resulting in different protein isoforms. Recently WHSC1 has been identified as a critical epigenetic regulator for Tfh differentiation.