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Species Reactivity
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Species Reactivity
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验证数据展示

  • WB analysis using 67725-1-Ig (same clone as 67725-1-PBS)

    WB analysis using 67725-1-Ig (same clone as 67725-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67725-1-Ig (WWOX antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67725-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 67725-1-Ig (same clone as 67725-1-PBS)

    IHC staining of mouse testis using 67725-1-Ig (same clone as 67725-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 67725-1-Ig (WWOX antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67725-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WWOX antibody included
  • Cytometric bead array standard curve of MP51258-1

    Cytometric bead array standard curve of MP51258-1

    Cytometric bead array standard curve of MP51258-1, WWOX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67725-2-PBS. Detection antibody: 67725-1-PBS. Standard:Ag7969. Range: 0.195-100 ng/mL.

WWOX Monoclonal antibody, PBS Only (Detector)

WWOX Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Cat No. 67725-1-PBS

Print datasheet

CloneNo. 1B8F4

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat, pig

Applications

WB, IHC, Cytometric bead array, Indirect ELISA

Synonyms

FRA16D, FOR1, FOR, EC:1.1.1.-, D16S432E

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy WWOX Ready-To-Use IHC Kit. WWOX primary antibody included.

产品信息

67725-1-PBS targets WWOX as part of a matched antibody pair:

MP51258-1: 67725-2-PBS capture and 67725-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, IHC, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen WWOX fusion protein Ag7969 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name WW domain containing oxidoreductase
Synonyms FRA16D, FOR1, FOR, EC:1.1.1.-, D16S432E
Calculated Molecular Weight 47 kDa
Observed Molecular Weight40 kDa
GenBank Accession NumberBC003184
Gene Symbol WWOX
Gene ID (NCBI) 51741
RRIDAB_2882911
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NZC7
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WWOX(WW domain-containing oxidoreductase) is also named as FOR, WOX1 and belongs to the short-chain dehydrogenases/reductases (SDR) family. The gene encodes a 46 kDa protein that contains two WW domains and a short-chain dehydrogenase/reductase domain and the protein is lost or reduced in the majority of many cancer types including breast, prostate, esophageal, lung, stomach, and pancreatic carcinomas and in a large fraction of other cancer types(PMID:17360458). WWOX behaves as a potential tumor-suppressor gene(PMID:15064722). It has 7 isoforms produced by alternative splicing.