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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of HepG2 using 28689-1-AP (same clone as 28689-1-PBS)

    WB analysis of HepG2 using 28689-1-AP (same clone as 28689-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 28689-1-AP (WWP1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28689-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 28689-1-AP (same clone as 28689-1-PBS)

    IHC staining of human breast cancer using 28689-1-AP (same clone as 28689-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 28689-1-AP (WWP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28689-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WWP1 antibody included
  • IHC staining of human breast cancer using 28689-1-AP (same clone as 28689-1-PBS)

    IHC staining of human breast cancer using 28689-1-AP (same clone as 28689-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 28689-1-AP (WWP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28689-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WWP1 antibody included

WWP1 Polyclonal antibody, PBS Only

WWP1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28689-1-PBS

Print datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy WWP1 Ready-To-Use IHC Kit. WWP1 primary antibody included.

产品信息

28689-1-PBS targets WWP1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen WWP1 fusion protein Ag30161 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name WW domain containing E3 ubiquitin protein ligase 1
Synonyms
Calculated Molecular Weight 922 aa, 105 kDa
Observed Molecular Weight 95-105 kDa
GenBank Accession NumberBC036065
Gene Symbol WWP1
Gene ID (NCBI) 11059
RRIDAB_2881195
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H0M0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is a multifunction protein containing an N-terminal C2 domain, four tandem WW domains for substrate binding, and a C-terminal catalytic HECT domain for ubiquitin transferring. It is also named as AIP5, Tiul1. WWP1 regulates a variety of cellular biological processes including protein trafficking and degradation, signaling, transcription, and viral budding. WWP1 has been implicated in several diseases, such as cancers, infectious diseases, neurological diseases, and aging(PMID:22051607). It has 6 isoforms produced by alternative splicing.