- Featured Product
- KD/KO Validated
CoraLite® Plus 488-conjugated ZAP70 Monoclonal antibody
ZAP70 Monoclonal Antibody for
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse, pig
Applications
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1A11G9
验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 60200-1-Ig
产品信息
CL488-60200 targets ZAP70 in applications and shows reactivity with human, mouse, pig samples.
| Tested Applications | Application Description |
| Tested Reactivity | human, mouse, pig |
| Immunogen | ZAP70 fusion protein Ag7943 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | zeta-chain (TCR) associated protein kinase 70kDa |
| Synonyms | 70 kDa zeta associated protein, FLJ17670, FLJ17679, SRK, STD, Syk related tyrosine kinase, Tyrosine protein kinase ZAP 70, TZK, ZAP 70, ZAP70 |
| Calculated Molecular Weight | 70 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC039039 |
| Gene Symbol | ZAP70 |
| Gene ID (NCBI) | 7535 |
| ENSEMBL Gene ID | ENSG00000115085 |
| RRID | AB_2919236 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P43403 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Zeta-associated protein (ZAP)-70, a member of the Syk family of tyrosine kinases, plays an important role in T-cell receptor signaling, natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.
