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验证数据展示

  • IF Staining of mouse small intestine using CL594-67389

    IF Staining of mouse small intestine using CL594-67389

    Immunofluorescent analysis of (4% PFA) fixed mouse small intestine tissue using CoraLite® Plus 594 ZG16 antibody (CL594-67389, Clone: 1A7B9 ) at dilution of 1:100, CoraLite® Plus 488 PIGR antibody (CL488-22024, green), Villin antibody (16488-1-AP, Magenta).

  • IF Staining of mouse small intestine using CL594-67389

    IF Staining of mouse small intestine using CL594-67389

    Immunofluorescent analysis of (4% PFA) fixed mouse small intestine tissue using CoraLite® Plus 594 ZG16 antibody (CL594-67389, Clone: 1A7B9 ) at dilution of 1:100, CoraLite® Plus 488 PIGR antibody (CL488-22024, green), Villin antibody (16488-1-AP, Magenta).

CoraLite® Plus 594-conjugated ZG16 Monoclonal antibody

ZG16 Monoclonal Antibody for IF-P
Cat No. CL594-67389

产品说明书

CloneNo. 1A7B9

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, pig, rat

应用

IF-P

别名

FLJ43571, FLJ92276, hZG16, JCLN, JCLN1, Secretory lectin ZG16, ZG16, ZG16A, Zymogen granule protein 16

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 594
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inmouse small intestine tissue
For other applications, we recommend the unconjugated version of this antibody, 67389-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-67389 targets ZG16 in IF-P applications and shows reactivity with Human, mouse, pig, rat samples.

经测试应用 IF-P Application Description
经测试反应性 Human, mouse, pig, rat
免疫原 ZG16 fusion protein Ag11332 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 zymogen granule protein 16 homolog (rat)
别名 FLJ43571, FLJ92276, hZG16, JCLN, JCLN1, Secretory lectin ZG16, ZG16, ZG16A, Zymogen granule protein 16
计算分子量 167 aa, 18 kDa
观测分子量 16 kDa
GenBank蛋白编号BC029149
基因名称 ZG16
Gene ID (NCBI) 653808
RRIDAB_3084764
偶联类型 CoraLite® Plus 594 Fluorescent Dye
最大激发/发射波长594 nm / 615 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDO60844
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Zymogen granule protein 16 (ZG16) has a Jacalin-like lectin domain, which is mainly expressed by mucus-secreting cells, including goblet cells in the intestine. It's reported that ZG16 expression was significantly decreased in colorectal cancer compared to normal tissue. ZG16 gene expression and copy number variations (CNV) were associated with multiple molecular and clinicopathological features of CRC including MSI, MLH1 silencing and so on. It's found that ZG16 is negatively correlated with lymphatic invasive and distant metastasis. Besides, overexpression of ZG16 blocks PD-L1 expression in colorectal cancer, and promotes NK cells survival and proliferation. Very importantly, ZG16 suppresses colorectal tumor growth via the immune system. (PMID: 33360840, 21893569)

实验方案

Product Specific Protocols
IF protocol for CL Plus 594 ZG16 antibody CL594-67389Download protocol
Standard Protocols
Click here to view our Standard Protocols