验证数据展示
产品信息
66178-1-PBS targets Zinc Alpha 2 Glycoprotein in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Zinc Alpha 2 Glycoprotein fusion protein Ag5661 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | alpha-2-glycoprotein 1, zinc-binding |
别名 | AZGP1, ZA2G, ZAG, Zinc alpha 2 glycoprotein, Zinc-alpha-2-glycoprotein, Zn alpha 2 glycoprotein, Zn alpha 2 GP, ZNGP1 |
计算分子量 | 298 aa, 34 kDa |
观测分子量 | 41 kDa |
GenBank蛋白编号 | BC033830 |
基因名称 | Zinc Alpha 2 Glycoprotein |
Gene ID (NCBI) | 563 |
RRID | AB_2881573 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P25311 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Zinc-alpha-2-glycoprotein (AZGP1), a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract, and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).