CoraLite® Plus 488-conjugated Alpha 1 antichymotrypsin Monoclonal antibody

Alpha 1 antichymotrypsin Monoclonal Antibody for IF-P
Cat No. CL488-66078

产品说明书

CloneNo. 3F2F10

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

IF-P

Alpha Antichymotrypsin, SERPINA3, ACT, AACT, A-1-Antichymotrypsin

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF-P detected inhuman tonsillitis tissue
Planning an IHC experiment? We recommend our IHCeasy SERPINA3/AACT Ready-To-Use IHC Kit. SERPINA3/AACT primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66078-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-66078 targets Alpha 1 antichymotrypsin in IF-P applications and shows reactivity with human samples.

经测试应用 IF-P Application Description
经测试反应性 human
免疫原 Alpha 1 antichymotrypsin fusion protein Ag2830 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
别名 Alpha Antichymotrypsin, SERPINA3, ACT, AACT, A-1-Antichymotrypsin
计算分子量 448 aa, 48 kDa
观测分子量 60 kDa
GenBank蛋白编号BC010530
基因名称 Alpha 1 Antichymotrypsin
Gene ID (NCBI) 12
RRIDAB_2883251
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP01011
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Alpha 1 antichymotrypsin antibody CL488-66078Download protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...