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CoraLite® Plus 488-conjugated Alpha Antichymotrypsin Monoclonal antibody

Alpha Antichymotrypsin Monoclonal Antibody for IF-P

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

3F2F10

Cat no : CL488-66078

Print datasheet

Synonyms

A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3

验证数据展示

  • IF Staining of human tonsillitis using CL488-66078

    IF Staining of human tonsillitis using CL488-66078

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CL488-66078 (alpha 1 Antichymotrypsin antibody) at dilution of 1:50.

经过测试的应用

Positive IF-P detected inhuman tonsillitis tissue
Planning an IHC experiment? We recommend our IHCeasy SERPINA3/AACT Ready-To-Use IHC Kit. SERPINA3/AACT primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66078-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of CL488-66078 is Alpha Antichymotrypsin Fusion Protein expressed in E. coli.

Tested Applications IF-P Application Description
Tested Reactivity human
Immunogen Alpha Antichymotrypsin fusion protein Ag2830 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Synonyms A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3
Calculated Molecular Weight 448 aa, 48 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC010530
Gene Symbol Alpha 1 Antichymotrypsin
Gene ID (NCBI) 12
RRIDAB_2883251
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP01011
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Alpha Antichymotrypsin antibody CL488-66078Download protocol
Standard Protocols
Click here to view our Standard Protocols