BDNF in synaptic transmission, neuronal survival, neurogenesis, and plasticity

Brain-derived neurotrophic factor (BDNF) plays a significant role in synaptic transmission, neuronal survival, neurogenesis, and plasticity. It participates in axonal growth, pathfinding, and the modulation of dendritic growth and morphology.

Recent studies have suggested that abnormalities in BDNF homeostasis contribute to brain pathogenesis and BDNF administration which leads to later-onset/slower neuropsychiatric disease progression (e.g., depression and bipolar disorder). Based on previous results it was also concluded that peripheral administration of BDNF in the early stage could have a therapeutic potential for neurodevelopmental diseases such as Rett syndrome.

KE00096 is a colorimetric solid-phase sandwich enzyme-linked immunosorbent assay (sandwich ELISA). The Proteintech BDNF ELISA Kit (KE00096) is a quantitative measurement of human endogenous BDNF protein in serum, plasma, and cell culture supernatant.

Product Focus:  Human BDNF ELISA Kit 
Catalog number:  KE00096 Assay type: Sandwich
Tests: 1 X 96 well plate Sample Type: Serum, Plasma, Cell culture supernatant

Human/Rat BDNF ELISA kit

  Assay range (pg/ml) Sensitivity (pg/ml)
Proteintech 12.5 - 800 0.14
Competitor 1 15.6 - 1000 2.4
Competitor 2 65.5 - 4000 20
Proteintech ELISA Kits

- Ready to use.

-  Guarantee of consistent results with high reproducibility.

-  Quantitative detection of proteins in serum, plasma, or in supernatant of cell lysates.

-  High sensitivity and broad assay range (standard curve R2 = 0.999).