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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
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验证数据展示

  • IHC staining of mouse heart using 18984-1-AP (same clone as 18984-1-PBS)

    IHC staining of mouse heart using 18984-1-AP (same clone as 18984-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 18984-1-AP (nNOS antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18984-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 18984-1-AP (same clone as 18984-1-PBS)

    IHC staining of mouse heart using 18984-1-AP (same clone as 18984-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 18984-1-AP (nNOS antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18984-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 18984-1-AP (same clone as 18984-1-PBS)

    IF Staining of mouse brain using 18984-1-AP (same clone as 18984-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using nNOS antibody (18984-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18984-1-PBS in a different storage buffer formulation.

nNOS Polyclonal antibody, PBS Only

nNOS Polyclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 18984-1-PBS

Print datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, IF-P, Indirect ELISA

Synonyms

NOS1, N-NOS, NC-NOS, NC NOS, N NOS

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

18984-1-PBS targets nNOS in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name nitric oxide synthase 1 (neuronal)
Synonyms NOS1, N-NOS, NC-NOS, NC NOS, N NOS
Calculated Molecular Weight 161 kDa
GenBank Accession NumberNM_000620
Gene Symbol nNOS
Gene ID (NCBI) 4842
RRIDAB_10598169
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP29475
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

nNOS belongs to the NOS family. nNOS produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. nNOS is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in nNOS gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1). The antibody can recognize isoform 1,2,4 of nNOS.