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p57Kip2 Monoclonal antibody, PBS Only

p57Kip2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A12H3

Cat no : 66794-1-PBS

Print datasheet

Synonyms

CDKN1C, KIP2, p57, Cyclin-dependent kinase inhibitor p57, Cyclin-dependent kinase inhibitor 1C

验证数据展示

  • WB analysis using 66794-1-Ig (same clone as 66794-1-PBS)

    WB analysis using 66794-1-Ig (same clone as 66794-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66794-1-Ig (CDKN1C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 66794-1-Ig (same clone as 66794-1-PBS)

    IHC staining of human placenta using 66794-1-Ig (same clone as 66794-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66794-1-Ig (p57Kip2 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CDKN1C antibody included
  • IHC staining of human placenta using 66794-1-Ig (same clone as 66794-1-PBS)

    IHC staining of human placenta using 66794-1-Ig (same clone as 66794-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66794-1-Ig (p57Kip2 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66794-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CDKN1C antibody included
Planning an IHC experiment? We recommend our IHCeasy CDKN1C Ready-To-Use IHC Kit. CDKN1C primary antibody included.

产品信息

66794-1-PBS targets p57Kip2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen p57Kip2 fusion protein Ag19927 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Synonyms CDKN1C, KIP2, p57, Cyclin-dependent kinase inhibitor p57, Cyclin-dependent kinase inhibitor 1C
Calculated Molecular Weight 316 aa, 32 kDa
Observed Molecular Weight 57 kDa
GenBank Accession NumberBC067842
Gene Symbol p57 Kip2/CDKN1C
Gene ID (NCBI) 1028
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP49918
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.