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Antibodies cited in Nature

Proteintech antibodies cited in Nature.

What matters to Proteintech is the success of its antibodies in the hands of scientists. Here’s just a small selection of recent high impact publications featuring Proteintech antibodies.

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Genome-embedded ribonucleotides are known as most abundant aberrant nucleotides in the genome of cycling cells. Zimmermann and colleagues suggest that manipulation of genomic ribonucleotide processing could be harnessed for therapeutic purposes and this strategy may expand the use of PARP inhibitors to some tumors that are proficient in homologous recombination.

Michal Zimmermann et al.

Nature volume 559, pages 285–289 (2018)

Pubmed ID:29973717

Application: WB

Species: human

Cited Antibody: RNASEH2C Antibody

Catalog number: 16518-1-AP

Immunohistochemical of paraffin-embedded human lung using 16518-1-AP(RNASEH2C antibody) at dilution of 1:50 (under 10x lens) HEK-293 cells were subjected to SDS PAGE followed by western blot with 16518-1-AP(RNASEH2C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours

 
Single-cell analysis of early progenitor cells that build coronary arteries

Investigation into cell fate conversion using single-cell RNA sequencing and mouse genetics of venous to arterial cells.

Tianying Su et al.

Nature volume 559, pages 356–362 (2018)

Pubmed ID: 29973725 

Application: IF

Species: mouse

Cited antibody: DACH1 Antibody

Catalog number: 10914-1-AP

KO validated

WB result of DACH1 (10914-1-AP, 1:4000) with si-control and si-DACH1 transfected HEK293 cells. Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HEK-293 cells using 10914-1-AP(DACH1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)