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LETM1 Monoclonal antibody, PBS Only (Detector)

LETM1 Monoclonal Antibody for WB, IF/ICC, Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, rat

Applications

WB, IF/ICC, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B9B9

Cat no : 68208-1-PBS

Print datasheet

Synonyms

Leucine zipper-EF-hand-containing transmembrane protein 1, 2B9B9



Planning an IHC experiment? We recommend our IHCeasy LETM1 Ready-To-Use IHC Kit. LETM1 primary antibody included.

产品信息

68208-1-PBS targets LETM1 as part of a matched antibody pair:

MP50653-2: 68208-4-PBS capture and 68208-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, IF/ICC, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, rat
Immunogen LETM1 fusion protein Ag8851 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name leucine zipper-EF-hand containing transmembrane protein 1
Synonyms Leucine zipper-EF-hand-containing transmembrane protein 1, 2B9B9
Calculated Molecular Weight 739 aa, 83 kDa
Observed Molecular Weight83 kDa
GenBank Accession NumberBC021208
Gene Symbol LETM1
Gene ID (NCBI) 3954
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO95202
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LETM1 is a mitochondrial inner membrane protein. It functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. It served as an anchor protein for complex formation between mitochondria and ribosome, and regulated mitochondrial biogenesis. It was also identified inWolf-Hirschhorn syndrome, and was deleted in nearly all patients with the syndrome. A recent study determined that adenovirus-mediated LETM1 may provide a useful target for designing lung tumor prevention and treatment.