Emerin Recombinant antibody
Emerin Recombinant Antibody for IF/ICC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
230089B1
验证数据展示
经过测试的应用
Positive IF detected in | HeLa cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
82888-1-RR targets Emerin in IF, ELISA applications and shows reactivity with Human samples.
Tested Applications | IF/ICC, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | Emerin fusion protein Ag0236 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | emerin |
Synonyms | EDMD, EMD, emerin, LEMD5, STA |
Calculated Molecular Weight | 34 kDa |
GenBank Accession Number | BC000738 |
Gene Symbol | EMD |
Gene ID (NCBI) | 2010 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P50402 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Emerin (Emery-Dreifuss muscular dystrophy) (EMD or EDMD), a serine-rich nuclear membrane protein, is a member of the nuclear lamina-associated protein family. EMD may mediate membrane anchorage to the cytoskeleton by stabilizing and promoting the formation of a nuclear actin cortical network. Defects in EMD gene are the cause of Emery-Dreifuss muscular dystrophy type 1 (EDMD1), a degenerative myopathy characterized by weakness and atrophy of muscle without involvement of the nervous system, early contractures of the elbows Achilles tendons and spine, and cardiomyopathy associated with cardiac conduction defects. EMD inhibits beta-catenin activity by preventing its accumulation in the nucleus and is involved in HIV-1 infection.
实验方案
Product Specific Protocols | |
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IF protocol for Emerin antibody 82888-1-RR | Download protocol |
FC protocol for Emerin antibody 82888-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |