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CoraLite® Plus 488-conjugated ADAMTS12 Polyclonal antibody
ADAMTS12 Polyclonal Antibody for IF/ICC
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
验证数据展示
经过测试的应用
Positive IF/ICC detected in | NIH/3T3 cells |
For other applications, we recommend the unconjugated version of this antibody, 24934-1-AP
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-24934 targets ADAMTS12 in IF/ICC applications and shows reactivity with human, mouse samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | human, mouse |
Immunogen | ADAMTS12 fusion protein Ag20712 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
Synonyms | ADAM-TS12, ADAM-TS 12, ADAMTS 12, ADAM TS12, ADAM TS 12 |
Calculated Molecular Weight | 178 kDa |
Observed Molecular Weight | 155 kDa |
GenBank Accession Number | BC058841 |
Gene Symbol | ADAMTS12 |
Gene ID (NCBI) | 81792 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P58397 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ADAMTS12(A disintegrin and metalloproteinase with thrombospondin motifs 12) is also named as AT12, ADAM-TS12, PRO4389 and belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. ADAMTS7 and ADAMTS12 appear to be potent negative regulators of endplate cartilage development(PMID:22247065). This protein has 3 isoforms produced by alternative splicing. The full length protein has 14 glycosylation sites.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 ADAMTS12 antibody CL488-24934 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |