• Featured Product
  • KD/KO验证

CoraLite® Plus 488-conjugated ADAMTS12 Polyclonal antibody

ADAMTS12 Polyclonal Antibody for IF/ICC
Cat No. CL488-24934

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF/ICC

ADAM-TS12, ADAM-TS 12, ADAMTS 12, ADAM TS12, ADAM TS 12

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inNIH/3T3 cells
For other applications, we recommend the unconjugated version of this antibody, 24934-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-24934 targets ADAMTS12 in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原 ADAMTS12 fusion protein Ag20712 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ADAM metallopeptidase with thrombospondin type 1 motif, 12
别名 ADAM-TS12, ADAM-TS 12, ADAMTS 12, ADAM TS12, ADAM TS 12
计算分子量 178 kDa
观测分子量 155 kDa
GenBank蛋白编号BC058841
基因名称 ADAMTS12
Gene ID (NCBI) 81792
RRIDAB_3672782
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP58397
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ADAMTS12(A disintegrin and metalloproteinase with thrombospondin motifs 12) is also named as AT12, ADAM-TS12, PRO4389 and belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. ADAMTS7 and ADAMTS12 appear to be potent negative regulators of endplate cartilage development(PMID:22247065). This protein has 3 isoforms produced by alternative splicing. The full length protein has 14 glycosylation sites.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 ADAMTS12 antibody CL488-24934Download protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...